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(S)-(+)-N-(2,3-Epoxipropyl)ftalimid

(S) N-glycidyl phthalimide, commonly referred to as (S) - N-PiP ((S) - N-phenylpyrrole-2-carboxamide

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Innehåll

(S) N-glycidyl phthalimide, commonly referred to as (S) - N-PiP ((S) - N-phenylpyrrole-2-carboxamide).

nature:

(S) N-glycidyl phthalimide is an organic compound. It is a colorless to light yellow crystal that is soluble in common organic solvents such as dimethyl sulfoxide and dichloromethane.

Purpose:

(S) N-glycidyl phthalimide is widely used in chiral organic synthesis as a precursor for chiral catalysts or ligands. It can be used for asymmetric synthesis reactions, such as asymmetric addition and asymmetric dehydration.

Manufacturing method:

(S) The preparation of N-glycidol phthalimide is usually achieved by first synthesizing (S) - N-glycidol ((S) - N-proline) and then reacting it with phthalimide. The specific preparation method can refer to relevant organic synthesis literature.

Security information:

(S) There are currently few reports on the safety information of N-glycidyl phthalimide, but as an organic compound, the following safety measures should generally be taken:

-Avoid contact with skin, eyes, or respiratory tract, and wear appropriate protective gloves, glasses, and masks.

-During the operation, it is necessary to prevent the generation of dust, smoke, or gas and maintain well ventilated laboratory conditions.

-Store in a dry and cool place, away from sources of fire and oxidants.

-Follow proper handling and disposal procedures to avoid harm to the environment.


Name(S)-(+)-Glycidyl Phthalimide
SynonymsRivaroxaban Impurity 39
(S)-Glycidyl Phthalimide
(S)-GLYCIDYL PHTHALIMIDE
(S)-N-Glycidylphthalimide
Diethyl (3-pyridyl) borane
N-(S)-Glycidylphthalimide
(S)-(+)-Glycidyl Phthalimide
(S)-(+)-GLYCIDYL PHTHALIMIDE
(S)-(+)-Glycidyl phthalimide
(S)-(+)-N-(2,3-Epoxipropyl)ftalimid
(S)-2-oxiranylmethyl-isoindole-1,3-dione
(S)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE
2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione
2-((2S)-oxiranylmethyl)-1H-isoindole-1,3(2H)-dione
2-((2S)-OXIRANYLMETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE
2-[(2S)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]-
CAS161596-47-0
EINECS1308068-626-2
InChIInChI=1/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2/t7-/m0/s1

Molecular FormulaC11H9NO3
Molarmassa203.19
Täthet1.446±0.06 g/cm3(Predicted)
Melting Point102 °C
Boling Point347.4±15.0 °C(Predicted)
Blixtpunkt163.9°C
SolubilityChloroform (Slightly), Ethyl Acetate (Slightly)
Vapor Presure0.001-2.17Pa at 25-90.25℃
UtseendeWhite powder
FärgVit
pKa-2.24±0.20(Predicted)
Lagringstillståndunder inert gas (nitrogen or Argon) at 2-8°C
SensitiveEasily absorbing moisture
Refractive Index10 ° (C=2.2, CHCl3)

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