107-94-8 - Names and IdentifiersName3-Chloropropionic acidSynonymsNSC 174HSDB 20533-chloropropa
E-postadress: info@standard-groups.com
| Name | 3-Chloropropionic acid |
| Synonyms | NSC 174 HSDB 2053 3-chloropropanoate 3-chloro-propionicaci 3-Chloropropanic acid 3-Chloropropionic acid β-Chloropropionic acid Dapoxetine impurity 27 3-Chloropropanoic acid acide3-chloropropanoique beta-Chloropropionic acid Propanoic acid, 3-chloro- Propionic acid, 3-chloro- Brexpiprazole Impurity 67 beta-monochloropropionicacid beta-Monochloropropionic acid |
| CAS | 107-94-8 |
| EINECS | 203-534-4 |
| InChI | InChI=1/C3H5ClO2/c4-2-1-3(5)6/h1-2H2,(H,5,6)/p-1 |
| InChIKey | QEYMMOKECZBKAC-UHFFFAOYSA-N |
| Molecular Formula | C3H5ClO2 |
| Molarmassa | 108.52 |
| Täthet | 1,27 g/cm3 |
| Melting Point | 37 °C |
| Boling Point | 203-205°C(lit.) |
| Blixtpunkt | >230°F |
| Vattenlöslighet | freely soluble |
| Solubility | H2O: soluble50mg/mL, clear, colorless |
| Vapor Presure | 0.147mmHg at 25°C |
| Utseende | Crystalline Low Melting Mass |
| Färg | White to beige |
| Merck | 14,2159 |
| BRN | 1098495 |
| pKa | 3.98(at 25℃) |
| Lagringstillstånd | Store below +30°C. |
| Refractive Index | 1.4380 (estimate) |
| Physical and Chemical Properties | physical and chemical properties: White Crystal melting point 37-41°C boiling point 203-205°C flash point 125°C water-soluble freely soluble |
| Use | For organic synthesis, medicine, dyes, pesticide intermediates. |
| Hazard Symbols | C - Corrosive |
| Risk Codes | R35 - Causes severe burns R34 - Causes burns R21/22 - Harmful in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3261 8/PG 2 |
| WGK Germany | 1 |
| RTECS | UE8750000 |
| FLUKA BRAND F CODES | 3-10 |
| TSCA | Yes |
| HS Code | 29159080 |
| Hazard Class | 8 |
| Packing Group | III |
| Raw Materials | Propionic acid |
| Downstream Products | 3-Chloropropionyl chloride |
| LogP | 0.41 |
| Use | organic synthesis intermediate for the production of anti-epileptic pain drugs. used as pesticide and pharmaceutical intermediates used in organic synthesis. |
| production method | There are a variety of preparation methods. Propionic acid is chlorinated to 3-chloropropionic acid at about 20 °c under ultraviolet light; Very small amounts of hydroquinone may also be added to the acrylic acid and then reacted below 20 °c with dry hydrogen chloride. The final product was obtained by distillation under reduced pressure. Further, acrylonitrile was added to hot hydrochloric acid, and the reaction was conducted under reflux for 6 hours. The reactant was cooled, the resulting ammonium chloride was filtered, extracted with diethyl ether, washed with 20% ammonium chloride solution to remove hydrochloric acid, and dried to recover diethyl ether, followed by distillation under reduced pressure to obtain 3-chloropropionic acid. 3-chloropropionic acid can also be prepared by reacting acrolein with hydrogen chloride to form chloropropionaldehyde, followed by nitric acid oxidation, or by nitric acid oxidation of 3-chloro-1-propanol. |
| category | corrosive article |
| toxicity grade | high toxicity |
| Acute toxicity | subcutaneous-mouse LDL0: 1040 mg/kg |
| flammability hazard characteristics | flammable; Toxic chloride smoke generated by heating |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored separately from oxidants and alkalis. |
| fire extinguishing agent | Sand, foam, water mist, carbon dioxide |
| Occupational Standard | SEL 5 mg/m3 |
Ansvarsfriskrivning: Ovanstående innehåll är endast för referens och kommunikation mellan branschinsider, och garanterar inte dess riktighet eller fullständighet. Enligt gällande lagar och förordningar och förordningar på denna webbplats ska enheter eller individer som köper relaterade artiklar erhålla giltiga kvalifikationer och kvalifikationsvillkor.
Företagstelefon
+86-21-6420 0566
Arbetstider
måndag till fredag
Mobiltelefon:
13816217984
E-post:
info@qinsun-lab.com
