2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone

2,3,4,6-tetra-O-trimethylsilyl-D-glucuronic acid lactone, commonly referred to as TMS-D-glucuronic acid lactone, is an organic compound. The following is an introduction to its properties, uses, manufacturing methods, and safety information:

nature:

Appearance: White crystalline solid.

Solubility: soluble in common organic solvents such as ether and dimethyl sulfoxide.

Purpose:

As a reagent in organic synthesis, TMS-D-glucuronic acid lactone is often used as a precursor for protecting groups (such as alcohol protecting groups) in organic synthesis, which can selectively protect alcohol groups.

Manufacturing method:

The preparation of TMS-D-glucuronic acid lactone is generally carried out through a synthetic pathway. The specific method includes reacting D-glucuronic acid lactone with trimethylchlorosilane to generate TMS-D-glucuronic acid lactone.

Security information:

TMS-D-glucuronic acid lactone is generally safe when following laboratory safety operating procedures. However, as an organic synthesis reagent, it still needs to be stored and used properly.

This compound may have a certain degree of irritation and sensitization to the human body, and appropriate protective measures should be taken when in contact, such as wearing gloves and goggles.

When using or handling TMS-D-glucuronic acid lactone, avoid inhalation, ingestion, or contact with skin, eyes, etc. If accidentally touched, immediately rinse the affected area with plenty of water and seek medical treatment. Follow relevant regulations to safely dispose of waste.