2-AMINO-3-HYDROXY-2-METHYLBUTANOIC ACID - Names and Identifiers
Name | 2-AMINO-3-HYDROXY-2-METHYLBUTANOIC ACID
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Synonyms | 3-hydroxyIsovaline Isovaline, 3-hydroxy- 2-AMINO-3-HYDROXY-2-METHYLBUTANOIC ACID (2R,3S)-2-aMino-3-hydroxy-2-Methylbutanoic acid (2R,3S)-2-amino-3-hydroxy-2-methylbutanoic acid
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CAS | 10148-74-0
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2-AMINO-3-HYDROXY-2-METHYLBUTANOIC ACID - Physico-chemical Properties
Molecular Formula | C5H11NO3
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Molarmassa | 133.15 |
Lagringstillstånd | 2–8°C |
2-AMINO-3-HYDROXY-2-METHYLBUTANOIC ACID - Introduction
(2R,3S)-2-amino-3-hydroxy-2-methylbutyric acid, also known as D-glycine, is a naturally occurring amino acid. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline powder
-Melting point: 230-233°C
-Solubility: Soluble in water, slightly soluble in alcohol
-Optical rotation:[α]D20 = 2.8 ° (c = 2, H2O)
-Molecular formula: C5H11NO3
-Molecular weight: 133.15g/mol
Use:
D-glycine has a wide range of applications in the fields of medicine and cosmetics:
-Medicine: D-glycine can be used in the synthesis of certain drugs, such as anti-diabetic drugs.
-Cosmetics: D-glycine can be used as a moisturizer and antioxidant in cosmetics.
Preparation Method:
The preparation of D-glycine can be carried out in a variety of ways. One common method is the synthesis catalyzed by amino acid dehydrogenase:
- D-glutamate dehydrogenase catalyzes the oxidation of glutamic acid to obtain L-cysteine;
- L-cysteine is then reduced by enzymes to produce D-glycine.
Safety Information:
D-Glycine is generally considered safe, with no clear reports of toxicity or carcinogenicity. However, as with any chemical substance, it is necessary to follow certain safe practices in its use and handling, such as wearing appropriate personal protective equipment and taking care to avoid inhalation and contact with skin or eyes. It is best to consult the relevant safety data sheet for detailed safety information before use.
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