Name: 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinoneCAS: 545445-44
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Synonyms: 3-Morpholin-4-yl-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydro-1H-pyridin-2-one Molecular Structure Molecular Formula: C20H25N3O3 Molecular Weight: 355.43 CAS Registry Number: 545445-44-1
5, 6-dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl) phenyl]-2(1H)-pyridone is one of the apixaban impurities. Apixaban (Apixaban) is an oral selective activation factor X inhibitor, jointly developed by Pfizer and Bristol-Myers Squibb. In January 2013, it obtained the import drug license issued by the State Food and Drug Administration of China, and was officially listed in China in April 2013.
| Name | 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone |
| Synonyms | HSK00001094 Apixaban Impurity P Apixaban Impurity H Apixaban Intermediates 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) 1-(4-(3-morpholino-2-oxocyclohex-3-enyl)phenyl)piperidin-2-one 3-Morpholino-1-[4-(2-oxo-1-piperidyl)phenyl]-5,6-dihydropyridin-2(1H)-one 3-morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one 5-morpholin-4-yl-1-[4-(2-oxopiperidin-1-yl)phenyl]-2,3-dihydropyridin-6-one 3-Morpholin-4-yl-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydro-1H-pyridin-2-one 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone |
| CAS | 545445-44-1 |
| EINECS | 1308068-626-2 |
| Molecular Formula | C20H25N3O3 |
| Molarmassa | 355.43 |
| Täthet | 1.267 |
| Melting Point | >199°C (dec.) |
| Boling Point | 625.0±55.0 °C(Predicted) |
| Blixtpunkt | 331.775 °C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Utseende | Solid |
| Färg | Pale Beige |
| pKa | 3.25±0.20(Predicted) |
| Lagringstillstånd | 2–8°C |
| Use | This product is for scientific research only and shall not be used for other purposes. |
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