Azathioprine

Molecular Formula: C9H7N7O2S Molecular Weight: 277.26 CAS No.: 446-86-6 An imidazole derivative of mercaptopurine, functions by decomposing into mercaptopurine in vivo. Its immune mechanism is the same as mercaptopurine, that is, it has purine antagonism. Because the immune active cells need purine substances in the proliferation period after antigen stimulation, giving purine antagonism at this time can inhibit the synthesis of DNA, RNA and protein, so as to inhibit the proliferation of lymphocytes, that is, prevent antigen sensitive lymphocytes from transforming into immune mother cells, and produce immune effect. Description This product is light yellow powder or crystalline powder; Odorless; It tastes slightly bitter. It is very slightly soluble in ethanol and almost insoluble in water; Soluble in dilute ammonia solution. Application Immunosuppressive drugs. It is a derivative of mercaptopurine, which decomposes into mercaptopurine in vivo and acts. It is mainly used to inhibit immune rejection in allogeneic transplantation, and is often combined with corticosteroids. It is also widely used in rheumatoid arthritis, systemic lupus erythematosus, autoimmune hemolytic anemia, thrombocytopenic purpura, active chronic hepatitis, ulcerative colitis, myasthenia gravis, scleroderma and other autoimmune diseases. Packing and Storage Preserve in tight, light-resistant containers. Minimum Order One package

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